Bio Folic Acid + B12 Liquid (30 Ml)

No reviews

Vegan combination of B vitamins • Helps the body form red blood cells and metabolize carbohydrates, fats and proteins • Helps reduce the risk of neural tube defects when taken daily before and during early pregnancy • Provides 400 mcg of folic acid and 125 mcg of vitamin B12 per 8 drops • Delicious natural cherry flavour Bio Folic Acid + B12 Liquid is a vegan option that helps prevent vitamin B12 deficiency in vegetarians and vegans, whose diets tend to provide inadequate levels of vitamin B12.1 Vitamin B12 and folic acid are both involved in red blood cell formation and DNA synthesis.2,3 Vitamin B12 and folic acid are also necessary for the conversion of homocysteine to methionine, which is needed for the production of S-adenosylmethionine, the methyl donor involved in almost all methylation reactions.4,5 Research demonstrates that daily supplementation with 400 mcg of folic acid during the first trimester helps reduce neural tube defects by approximately 50%.6 In a randomized placebo-controlled trial of 119 pregnant women, continuous supplementation with 400 mcg of folic acid per day during the second and third trimesters significantly increased maternal and cord blood folate status.7 Folic acid intake also helped to better maintain homocysteine levels in the later stages of pregnancy, which may be associated with appropriate methyl transfer activity.5,7 References 1. Briani, C, Dalla Torre, C, Citton, V, Manara, R, Pompanin, S, Binotto, G, Adami, F. Nutrients. 2013, 5: 4521-4539. 2. Fenech, M. Mutation Research. 2012, 733: 21-33. 4. Czeizel, AE, Dudàs, I, Vereczkey, A, Bánhidy, F. Nutrients. 2013, 5: 4760-4775.

5. Imbard, A, Benoist, JF, Blom, HJ. Int. J. Environ. Res. Public Health. 2013, 10: 4352-4389.

6. Osterhues, A, Ali, N.-É., Michels, KB.
Critical Reviews in Food Science and Nutrition. 2013, 53: 1180-1190.

7. McNulty, B, McNulty, H, Marshall, B, Ward, M, Molloy, AM, Scott, JM, Dornan, J, Pentieva, K. Am J Clin Nutr. 2013, 98: 92-98.