Genestra Brands
Herbolax (90 Veggie Caps)
Short-term relief of occasional constipation • Stimulant laxative • Promotes bowel movements by direct action on the large intestine • Includes a blend of senna, Chinese rhubarb, anise, fenugreek, and Cascara Sagrada Improved Formula • Now available in convenient vegetable capsules Herbolax is a herbal combination that provides short-term relief for occasional constipation. It includes the stimulant laxative senna, which promotes bowel movements through direct action on the large intestine. Senna’s bioactive compounds, members of the anthraquinone family, work by regulating colonic water reabsorption and motility.1 Preclinical research suggests that they decrease water reabsorption in the colon and promote electrolyte secretion into the colon to increase fecal water content.1 By stimulating the myenteric plexus, an important nerve center that coordinates peristalsis in the gastrointestinal tract, these compounds also increase bowel motility.2 Together, these actions help to produce soft stools and reduce transit time to facilitate defecation.2 In addition to providing senna, Herbolax features other anthraquinone-containing herbs, including rhubarb and cascara, along with a blend of anise and fenugreek. Anise contains the bioactive compound anethole, while fenugreek seeds are known for their high mucilaginous fiber content.3 References 1. Sandler, RB, Person, B, Raju, R. (2006) Medical Treatment of Constipation. In: Wexner, SD, Duthie, GS. (eds), Constipation. Springer, London. 2. Portalatin, M, Winstead, N. Clin Colon Rectal Surg. 2012, 25(1): 12-19. 3. Barnes, J, Anderson, LA, Phillipson, JD. (2007). Herbal Medicines (3rd ed.). London, UK: Pharmaceutical Press.
