Hmf Capsules (60 Caps)

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Promotes healthy, natural gut flora • Helps support gastrointestinal health • Provides 10 billion CFU per daily dose from: Lactobacillus acidophilus (CUL-60), Lactobacillus acidophilus (CUL-21), Bifidobacterium bifidum (CUL-20), Bifidobacterium animalis subsp. lactis (CUL-34) HMF capsules provide four human-sourced, proprietary probiotic strains that temporarily modify gut flora in adults and children. The composition of the intestinal microflora is relatively stable, although it can be altered by diet, stress, age, and medications.1 Probiotics promote the presence of beneficial bacteria to maintain healthy intestines.1 In addition to decreasing the survival of pathogens by increasing the release of antimicrobial peptides from host cells, probiotics also strengthen the epithelial barrier.2 They are involved in the integrity of tight junctions, which control permeability, and increase the release of mucin, which prevents pathogens from adhering to intestinal surface cells.2 Lactobacilli and bifidobacteria are the most commonly used probiotics and are safe for adults and children.2 They effectively colonize the intestines and decrease the movement of bacteria from the intestines into the circulation.2 Supplementing with large numbers of a combination of microorganisms helps to maximize intestinal colonization, promoting the growth of beneficial bacteria.3 In a randomized, placebo-controlled trial of 22 adults, daily probiotic supplementation containing Lactobacillus acidophilus (CUL-60 and CUL-21) catalyzed the restoration of the microflora after it had been altered by antibiotics.4 Similarly, a probiotic supplement containing CUL-21 can also significantly colonize the intestines of healthy adults.5 REFERENCES 1. Nagpal, R, Yadav, H, Kumar, M, Jain, S, Yamashiro, Y, Marotta, F. (2013). Probiotics and Prebiotics in Foods, Nutrition and Health (pp. 1-24). Boca Raton, FL: CRC Press. 2. Saulnier, N, Zocco, MA, Di Caro, S, Gasbarrini, G, Gasbarrini, A. Genes Nutr. 2006, 1(2): 107-116. 3. Allen, SJ, Wareham, K, Bradley, C, Harris, W, Dhar, A, Brown, H, Foden, A, Cheung, WY, Gravenor, MB, Plummer, S, Phillips, CJ, Mack, D. BMC Infect Dis. 2012, 12: 108. 4. Madden, JAJ, Plummer, SF, Tang, J, Garaiova, I, Plummer, NT, Herbison, M, Hunter, JO, Shimada, T, Cheng, L, Shirakawa, T. Int Immunopharmacol. 2005, 5: 1091-1097. 5. Mahenthiralingam, E, Marchbank, A, Drevinek, P, Garaiova, I, Plummer, S. BMC Microbiol. 2009, 9: 251.